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Jobs in South San Francisco, United States

518 open roles read nightly from companies’ own hiring pages. Each one links to the original ad.

Jobs in South San Francisco at a glance

Open roles
518
Remote
3%
Posted in the last 30 days
133
Advertised pay, middle half
$170K – $250Kmedian $210K

From the 450 jobs here that state yearly pay in USD: the top of each advertised range. Updated nightly.

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101–120 of 518 jobs

SortNewestHighest pay
  • Zipline · South San Francisco, California, United States

    $36.00 – $50.00 an hourTrades & logistics

    Zipline builds and operates autonomous delivery systems that move critical goods reliably and safely. The Avionics team develops and supports the electronics, sensors, communications hardware, wiring, and electromechanical assemblies used across our aircraft, droids, and ground…

  • Zipline · South San Francisco, California, United States

    Senior

    As the PLM & Configuration Lead on our Configuration & Change Management team, you will define and own the configuration management framework that ensures product integrity from early engineering development through mass production and field operations. You will set the…

  • Zipline · Esparto, California, United States +2

    $96.3K – $134K a yearEngineering

    The Mobile Test Site Project Manager owns the strategy, organization, readiness, and deployment of Zipline’s mobile test sites. These sites allow Flight Test to access environmental and operational conditions that cannot be consistently reproduced at Zipline’s permanent…

  • Zipline · South San Francisco, California, United States

    Senior$160K – $180K a yearEngineering

    As a Senior Manufacturing Engineer, you will turn complex electro-mechanical products into safe, reliable, repeatable production lines for Zipline’s aircraft, docks, and logistics hardware. You will own assigned final assembly and feeder sub-assembly lines from process…

  • Zipline · South San Francisco, California, United States

    Lead / staff$175K – $255K a yearEngineering

    Are you eager to apply your technical skills to solve real-world problems and drive meaningful change? Do you thrive in environments where you're given ownership, creative freedom, and complex challenges to tackle? If so, join the engineering team at Zipline—where your work…

  • Zipline · South San Francisco, California, United States

    Lead / staff$160K – $255K a yearEngineering

    Zipline’s autonomous drone delivery is a marvel of precision engineering—but it only works if the power stays on. We are looking for a hands-on, commercially-minded Electrical Systems Engineer to own the "backbone" of our charging towers.

  • Zipline · South San Francisco, California, United States

    Lead / staff$170K – $255K a yearEngineering

    Zipline builds and operates autonomous delivery systems that move critical goods reliably and safely. Dropbox is our customer-facing package-loading product that integrates mechatronics, sensors, electronics, access control, user interaction, firmware, and environmental…

  • Zipline · South San Francisco, California, United States

    Lead / staff$170K – $255K a yearEngineering

    Zipline designs, manufactures, and operates autonomous delivery systems that depend on reliable avionics, sensing, communications, power, and ground-support hardware. These systems must work in the real world, at fleet scale, across changing environments, manufacturing…

  • Zipline · South San Francisco, California, United States

    Senior$170K – $245K a yearEngineering

    Zipline is seeking a senior-level electrical engineer to lead the design and development of high-performance power electronics systems that support our drone charging and docking infrastructure.

  • Zipline · South San Francisco, California, United States

    Lead / staff$185K – $255K a yearEngineering

    Zipline is seeking a senior-level electrical engineer to lead the design and development of high-reliability embedded systems that support our drone charging and docking infrastructure.

  • Zipline · South San Francisco, California, United States

    Entry level$140K – $186K a yearEngineering

    Zipline designs, manufactures, and operates autonomous delivery systems that depend on reliable avionics, sensing, communications, power, and ground-support hardware. These systems must work in the real world, at fleet scale, across changing environments, manufacturing…

  • insitro · South San Francisco, California, United States

    HybridFull-timeDirector$217K – $231K a yearFinance

    insitro is a physical AI company dedicated to unlocking causal human biology and accelerating the delivery of better medicines to patients. Our unique Virtual Human™ platform identifies novel, high-impact genetic intervention points, which our TherML™ platform translates into…

  • Zipline · South San Francisco, California, United States

    Manager$160K – $235K a yearEngineering

    The Long Range Platform brings together aircraft, ground systems, software, manufacturing, and operations in one integrated product. We’re looking for a Mechanical Engineering Manager to set mechanical engineering strategy for the platform and lead the team responsible for…

  • SFMOMA · South San Francisco, California, United States +1

    On-siteFull-time$92.7K – $102.4K a yearDesign

    Manage team members based at the Museum’s Third Street location and the Collections Center. Partner with the Director of Collections Management and other department managers in sustaining a collections management community where all experts have a productive forum to share…

  • NewLimit · South San Francisco, California, United States

    Senior$130K – $171K a yearScience & research

    NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat aging by reprogramming the epigenome, a new therapeutic mechanism to restore youthful function in aged cells. We’ve built the world’s leading experimental and…

  • Twist Bioscience · South San Francisco, California, United States

    Senior$119K – $146.5K a yearFinance

    Build: models, reports, and systems; Own production of the corporate close and forecast cycle, including scenario setup, allocations, consolidation, and the reporting package; Serve as the team's OneStream power user, keeping the system reliable and the team productive; Build…

  • Twist Bioscience · South San Francisco, California, United States

    Manager$150K – $175K a yearOperations

    We are looking for an experienced Manager of Quality Management Systems to build, maintain, and improve our ISO 13485-certified QMS. In this role, you will own our internal and external audit program and our quality training program. You will keep the QMS compliant across all…

  • Xaira Therapeutics · South San Francisco, California, United States

    Lead / staff$164K – $205K a yearScience & research

    We are looking for a Principal Scientist with a strong background in immunology to identify new therapeutic opportunities and help shape Xaira’s portfolio.

  • Calico · South San Francisco, California, United States

    Mid level$105K – $115K a yearScience & research

    Calico is seeking an exceptional and experienced Lab Operations Specialist who will work within the Facilities and Operations group. The candidate will also work closely with the research groups and scientists and with other functional groups at Calico.

  • Director, IT

    3 weeks ago

    Lakefront Biotherapeutics, Inc. · South San Francisco, California, United States

    Director$230K – $250K a yearIT

    The Director of IT runs day-to-day technology operations for Lakefront Bio and leads delivery of the IT roadmap set with the Vice President of IT. This is a hands-on leadership role. You will own end-user services, business application support, and the compliance posture of our…

Updated 07 Nov 2026 10:21 UTC from the OptiTalent job library.