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Jobs in South San Francisco, United States

518 open roles read nightly from companies’ own hiring pages. Each one links to the original ad.

Jobs in South San Francisco at a glance

Open roles
518
Remote
3%
Posted in the last 30 days
133
Advertised pay, middle half
$170K – $250Kmedian $210K

From the 450 jobs here that state yearly pay in USD: the top of each advertised range. Updated nightly.

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61–80 of 518 jobs

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  • Zipline · South San Francisco, California, United States

    Lead / staff$160K – $250K a yearEngineering

    Zipline aircraft depend on embedded firmware to execute critical flight and safety functions across a network of microcontrollers and embedded Linux computers. This software must perform reliably as aircraft move from manufacturing into delivery operations at field sites around…

  • Zipline · South San Francisco, California, United States

    Senior$160K – $250K a yearEngineering

    Zipline aircraft depend on embedded firmware to execute critical flight and safety functions across a network of microcontrollers and embedded Linux computers. This software must perform reliably as aircraft move from manufacturing into delivery operations at field sites around…

  • Calico · South San Francisco, California, United States

    Lead / staff$197K – $220K a yearScience & research

    Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise…

  • Stripe · South San Francisco, California, United States

    $156.8K – $235.2K a yearEngineering

    Contribute to team strategy, roadmap, tooling process, and culture.; Scope, design, implement, and deploy robust solutions.; Make appropriate tradeoffs between reliability throughput, latency, resiliency, engineering, velocity and cost.; Innovate, design, and implement software…

  • Stripe · South San Francisco, California, United States

    $156.8K – $235.2K a yearEngineering

    Design, implement, test, deploy, and maintain backend services that support internal infrastructure and microservice operations.; Develop automation and tooling that streamlines resource provisioning, deployments, and operational workflows for internal engineering teams.;…

  • Erasca · San Diego, California, United States +1

    RemoteExecutive$275K – $355K a yearLegal & compliance

    Reporting to the Chief Regulatory Affairs Officer, the Executive Director or VP, Regulatory Affairs will lead regulatory strategy for defined disease area and develop and execute global regulatory strategies and submissions from pre-IND through regulatory approval to launch,…

  • Erasca · San Diego, California, United States +1

    RemoteDirector$185K – $200K a yearOperations

    Reporting to the Chief Regulatory Affairs Officer, the Sr Manager or Associate Director, Regulatory Operations will lead regulatory operations across the portfolio. This individual will build and manage the Regulatory Information Management System, lead submission planning and…

  • Xaira Therapeutics · South San Francisco, California, United States

    Senior$101K – $126K a yearScience & research

    We are seeking a highly motivated Senior Associate Scientist to join our High-Throughput Protein Production team and play a key role in automating, streamlining, and scaling up protein production processes. This position offers a unique opportunity to leverage your expertise in…

  • Zipline · South San Francisco, California, United States

    Lead / staff$210K – $260K a yearEngineering

    Autonomous aircraft need onboard software that communicates, updates, reports health, and recovers predictably in safety-critical environments. The Embedded Platform team builds the middleware and infrastructure beneath the flight software stack on embedded Linux systems.

  • Zipline · Ann Arbor, Michigan, United States +1

    Lead / staff$220K – $260K a yearEngineering

    The Routing team determines how every Zipline aircraft moves through the world. You will design safe and efficient flight paths that guide Zips through complex, ever-changing airspace - navigating obstacles, uncertainty, and dynamic conditions in real time, with your work…

  • Xaira Therapeutics · South San Francisco, California, United States

    Senior$136K – $170K a yearScience & research

    As a Senior Scientist on Xaira’s High-throughput Biology team, you will invent and develop single-cell assays for AI-driven drug discovery. You will create new molecular readouts and extend commercial and published technologies to measure cellular state and responses at scale.…

  • Zipline · South San Francisco, California, United States

    $160K – $205K a yearOperations

    Zipline is looking for a Technical Program Manager, Facilities to deliver the spaces and infrastructure that support our engineering, test, manufacturing, and workplace teams. You will lead facilities projects from initial requirements and feasibility through design,…

  • Acadia Pharmaceuticals Inc. · South San Francisco, California, United States

    Manager$168K – $210K a yearSales

    The Regional Sales Manager (RSM) is responsible for leading, developing, and holding accountable a team of Specialty Sales Specialists to consistently achieve sales goals. This includes hiring, coaching, performance management, and ensuring execution of sales strategies in…

  • NewLimit · South San Francisco, California, United States

    Lead / staff$180K – $240K a yearScience & research

    NewLimit is seeking an immunologist with leadership experience in therapeutics to lead our Immunology team. Our Immunology program is developing reprogramming medicines to restore youthful function in aged T cells for the treatment of inflammatory & infectious diseases with a…

  • Zipline · South San Francisco, California, United States

    Trades & logistics

    Have you ever had the experience of buying a product and having it break or become defective out of the box quickly and vow you never want to experience that again? If yes, this could be the position for you! As a critical member of the Structural Testing team, you will be part…

  • Xaira Therapeutics · South San Francisco, California, United States

    On-site$150K – $185K a yearEngineering

    We are building a next-generation lab automation and robotics platform that brings together robotic systems, simulation, computer vision, and AI to improve the speed, reliability, reproducibility, and scale of experimental biology.

  • insitro · South San Francisco, California, United States

    HybridFull-timeExecutive$300K – $345K a yearFinance

    insitro is looking for a senior finance leader to build and run our FP&A function, and to take what is already an AI-forward finance capability into the next generation of FP&A. We've done the work of embedding AI across finance; this role owns taking that foundation further so…

  • Aechelon Technology · South San Francisco, California, United States

    Lead / staff$166K – $249K a yearEngineering

    Lead the design, development, testing, optimization, and maintenance of C++ tools; Design, write, and update Python tools and scripts to enhance and automate areas of our production pipeline; Collaborate and communicate effectively with artists, engineers, producers, and…

  • Aechelon Technology · South San Francisco, California, United States

    Senior$133.3K – $199.9K a yearEngineering

    Own the design, development, testing, optimization, and maintenance of C++ tools; Design, write, and update Python tools and scripts to enhance and automate areas of our production pipeline; Collaborate and communicate effectively with artists, engineers, producers, and testers…

  • NewLimit · South San Francisco, California, United States

    Entry level$120K – $155K a yearScience & research

    We are seeking a Scientist to lead downstream process development for the mRNA Engineering team. In this role, you will design, optimize, and scale purification processes for mRNA drug substance.

Updated 07 Nov 2026 10:21 UTC from the OptiTalent job library.