OptiTalent · Job Finder
Jobs in South San Francisco, United States
518 open roles read nightly from companies’ own hiring pages. Each one links to the original ad.
Jobs in South San Francisco at a glance
- Open roles
- 518
- Remote
- 3%
- Posted in the last 30 days
- 133
- Advertised pay, middle half
- $170K – $250Kmedian $210K
From the 450 jobs here that state yearly pay in USD: the top of each advertised range. Updated nightly.
Hiring most here
- Zipline 198
- Neuralink 35
- Xaira Therapeutics 29
- Twist Bioscience 22
- Calico 20
By function
See which of these roles fit you: OptiTalent Career reads each ad against your own record, on your computer. About OptiTalent Career →
381–400 of 518 jobs
Counsel, Land Use
3 months agoZipline · South San Francisco, California, United States
$160K – $200K a yearLegal & complianceZipline is entering a period of rapid expansion across the U.S., and we’re seeking a seasoned Land Use Counsel to lead our efforts in securing and maintaining land use and zoning approvals for customer sites and charging infrastructure nationwide. This role sits at the…
Add your resume to Vilya's talent database!
3 months agoVilya · Seattle, Washington, United States +1
Vilya is a Series A biotech startup, co-founded by Nobel Prize-winning scientist David Baker. We're advancing beyond nature's limitations, designing novel peptides through computation to target disease biology with intention and precision. Every employee here plays a direct…
Senior / Staff Cloud Platform Engineer (ML)
3 months agoCalico · South San Francisco, California, United States
Lead / staff$220K – $290K a yearEngineeringCalico seeks a Senior / Staff Cloud Engineer to lead the execution and operation of our next-generation machine learning (ML) platform. As the technical authority for our Google Cloud Platform (GCP) environment, you will build infrastructure-as-Code (IaC), design secure…
Lead/ Senior Automation Engineer
3 months agoinsitro · South San Francisco, California, United States
On-siteFull-timeLead / staff$147K – $183K a yearEngineeringinsitro is a physical AI company dedicated to unlocking causal human biology and accelerating the delivery of better medicines to patients. Our unique Virtual Human™ platform identifies novel, high-impact genetic intervention points, which our TherML™ platform translates into…
Autonomy Droid Perception SWE - Offboard Systems
3 months agoZipline · Ann Arbor, Michigan, United States +1
Senior$200K – $240K a yearZipline is operating the world’s largest autonomous logistics network—delivering critical medical and commercial goods globally with high reliability, precision, and scale. As we expand into increasingly complex, safety-critical environments, the systems behind our autonomy…
Material Planning Manager
3 months agoZipline · South San Francisco, California, United States
On-siteSenior$118K – $259K a yearOperationsYou will own material planning and data integrity for a major system that supports Zipline’s drone delivery network. This role sits at the intersection of Engineering, Supplier Industrialization, Manufacturing, and Integrated Planning and is accountable for keeping production…
Senior Mechanical Engineer, Long Range Platform
3 months agoZipline · South San Francisco, California, United States
Senior$145K – $220K a yearEngineeringYou are an owner-oriented Mechanical Engineer joining Zipline’s Long Range Platform team to design, validate, and deliver critical airframe and electromechanical hardware used in long-distance autonomous delivery aircraft. This role sits at the intersection of field logistics,…
Mechanical Test Engineer, Motors (Senior)
3 months agoZipline · South San Francisco, California, United States
Senior$135K – $195K a yearEngineeringZipline’s aircraft rely on electric propulsion and actuation hardware that performs predictably in demanding conditions. As a Senior Motor Test Engineer, you will build the evidence behind that confidence by characterizing motors, propulsion systems, actuators, and propeller…
Zipline · South San Francisco, California, United States
Senior$124K – $210K a yearEngineeringYou will be Zipline’s Technical Program Manager for Flight Systems Platform, partnering across Flight Software, Cloud Infrastructure, Data and ML, Autonomy, Maps, Validation, Application Software, and Operations.
Global Supply Manager
3 months agoZipline · South San Francisco, California, United States
On-site$121.8K – $251K a yearOperationsWe’re hiring a Global Supply Manager to own end-to-end commodity strategy and supplier performance for mission-critical hardware that enables Zipline’s autonomous aircraft and global delivery operations. You will operate at the intersection of manufacturing ramp execution,…
Field Systems Engineer Pipeline
3 months agoZipline · South San Francisco, California, United States
$97K – $160K a yearEngineeringField Systems Engineering sits at the intersection of Engineering and Operations. We are responsible for understanding how Platform 2 performs in the real world, resolving its hardest technical problems, and turning what we learn into lasting improvements to the product and the…
Senior Mechanical Engineer - Stress Analysis
3 months agoZipline · South San Francisco, California, United States
Senior$145K – $220K a yearEngineeringYou are a hands-on Senior Structural Engineer owning aircraft structural analysis, system level Global Finite Element Models (GFEMs), and assembly level Detailed Finite Element Models (DFEMs). At Zipline you will apply first-principles analysis and tight design-test-analysis…
Head of Systems Engineering
3 months agoZipline · South San Francisco, California, United States
Director$225K – $275K a yearEngineeringYou will lead the systems engineering team responsible for defining the product capabilities roadmap, decomposing those capabilities into concrete architectures engineering teams can deliver on, and system validation & verification of new capabilities across our current…
Senior Mechanical Engineer, Autonomous Vehicles
3 months agoAeroVect · South San Francisco, California, United States
Full-timeSenior$144K – $180K a yearEngineeringAs a Senior Mechanical Engineer, you’ll design and integrate mechanical systems that enable autonomous driving on production vehicles. You’ll take full ownership of projects, from concept to integration, working hands-on to bring robust, production-ready solutions to life. This…
Senior Systems Engineer
3 months agoZipline · South San Francisco, California, United States
Senior$133K – $220K a yearEngineeringWe’re looking for a Senior Systems Engineer to join our team who has developed, tested, and deployed complex electromechanical systems into safety critical environments. Do you enjoy tackling the most cross-disciplinary parts of a complex program? Do you thrive in solving…
Senior RF Desense Engineer
3 months agoZipline · South San Francisco, California, United States
Senior$160K – $260K a yearEngineeringZipline is seeking a Senior RF Desense Engineer to lead the architecture, analysis, mitigation, validation, and long-term improvement of RF desense performance across our autonomous aircraft and ground infrastructure.
Senior/Staff Field Systems Engineer – RF Systems
3 months agoZipline · South San Francisco, California, United States
Lead / staff$160K – $200K a yearEngineeringZipline builds and operates autonomous delivery systems that move critical goods reliably and safely. These systems depend on RF links, antennas, embedded electronics, mechanical integration, networking, and navigation software working together across aircraft, droids, docks,…
RF Engineer - Avionics (All Levels)
3 months agoZipline · South San Francisco, California, United States
Mid level$130K – $200K a yearEngineeringThe Avionics team is a group of hardware and software experts responsible for designing robust systems that control our life-saving drone delivery service in some of the toughest environments on Earth. Our team designs aircraft avionics that must excel in a wide range of harsh,…
Senior Motion Planning Software Engineer
3 months agoZipline · Ann Arbor, Michigan, United States +1
Senior$190K – $230K a yearEngineeringZipline operates the world’s largest autonomous logistics system (ground or air) — and in the coming year, we will be hyper-scaling from thousands to tens of thousands of carefully coordinated drone deliveries in several dense, dynamic U.S. metros. Our Autonomy Motion Planning…
Simulation Software Engineer
3 months agoZipline · Ann Arbor, Michigan, United States +1
On-siteMid level$180K – $220K a yearEngineeringZipline is scaling the world's largest autonomous drone delivery network—a pioneering Physical AI system—delivering life-saving medical supplies and commercial goods globally. Our commitment to safety and exponential scale demands an industrial-grade virtual test environment,…
Updated 07 Nov 2026 10:21 UTC from the OptiTalent job library.