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Science jobs in California, United States

886 open roles read nightly from companies’ own hiring pages. Each one links to the original ad.

Science jobs in California at a glance

Open roles
886
Remote
7%
Posted in the last 30 days
235
Advertised pay, middle half
$126K – $300Kmedian $190K

From the 708 science jobs here that state yearly pay in USD: the top of each advertised range. Updated nightly.

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421–440 of 886 jobs

SortNewestHighest pay
  • Capable Labs · San Francisco, California, United States

    On-siteFull-timeFrom $500.00 a monthScience & research

    You will synthesize, purify, and characterize compounds for Capable’s small-molecule and adjacent therapeutic programs. You will own defined chemistry from route planning through material ready for biological testing, troubleshoot reactions and instruments, and contribute…

  • Twist Bioscience · South San Francisco, California, United States

    Senior$150.7K – $180.8K a yearScience & research

    Twist is seeking a Senior or Staff Computational Scientist to develop AI and computational solutions for protein design, discovery, and characterization.

  • Capable Labs · San Francisco, California, United States

    On-siteFull-timeFrom $500.00 a monthScience & research

    You will originate and lead new therapeutic programs from scientific concept through early validation. You will identify ambitious opportunities, turn them into testable programs with clear targets, modalities, assays, biomarkers, budgets, timelines, and kill criteria, and stay…

  • Capable Labs · San Francisco, California, United States

    On-siteFull-timeFrom $500.00 a monthScience & research

    You will lead RNA-therapeutics programs from target biology and oligonucleotide design through chemistry selection, assay strategy, quality control, and in vivo validation. You will build coherent programs—not isolated sequences—by connecting mechanism, tissue, potency,…

  • Capable Labs · San Francisco, California, United States

    On-siteFull-timeFrom $500.00 a monthScience & research

    You will support mouse studies and vivarium operations on a dedicated night-shift schedule, enabling overnight timepoints and around-the-clock study execution. You will perform careful animal work, collect and preserve samples for the day team, monitor animal welfare, and leave…

  • Capable Labs · San Francisco, California, United States

    On-siteFull-timeFrom $500.00 a monthScience & research

    You will support the day-to-day execution of mouse studies used to evaluate potential therapies for safety and effectiveness. You will perform careful animal work, maintain a clean and reliable vivarium, collect and organize study samples and records, and help the in vivo team…

  • Capable Labs · San Francisco, California, United States

    On-siteFull-timeFrom $500.00 a monthScience & research

    You will run peptide-synthesis workflows on a dedicated night-shift schedule so compounds are ready for characterization, biological testing, or handoff the next day. You will own careful overnight execution, troubleshoot issues independently, maintain complete records, and…

  • Capable Labs · San Francisco, California, United States

    On-siteFull-timeFrom $500.00 a monthScience & research

    You will lead peptide design and synthesis from sequence selection through production, purification, quality control, and biological handoff. You will own difficult chemistry and analytical problems, scale reliable workflows, and use SAR and biological results to help decide…

  • Capable Labs · San Francisco, California, United States

    On-siteFull-timeFrom $500.00 a monthScience & research

    You will lead peptide-chemistry execution on a dedicated night-shift schedule, keeping synthesis, purification, characterization, and biological handoffs moving around the clock. You will make sound technical decisions independently, solve difficult chemistry and instrument…

  • Capable Labs · San Francisco, California, United States

    On-siteFull-timeFrom $500.00 a monthScience & research

    You will make and characterize peptide candidates that move directly into biological testing. You will execute the full synthesis workflow—from resin loading through purification, quality control, and sample handoff—while troubleshooting failures and contributing observations…

  • Alector · South San Francisco, California, United States

    On-siteFull-timeSenior$125K – $140K a yearScience & research

    Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. By harnessing advancements in genetics, immunology and neuroscience, we…

  • Matter Intelligence · San Francisco, California, United States

    On-siteFull-timeScience & research

    Insurance is one of Matter’s first commercial verticals. We are working with leading property and casualty carriers to transform how they operate with data products that reveal real roof condition, material degradation, and hazard exposure at scale. We are looking for a Product…

  • Generalist · San Mateo, California, United States

    On-siteFull-time$240K – $350K a yearScience & research

    Pretraining gives us a general model. Post-training makes it useful, controllable, safe, and performant in the real world. You will train large pretrained robot models into production-ready systems via fine-tuning, reinforcement learning, steering, human feedback, task…

  • Anthropic · San Francisco, California, United States

    On-siteManager$405K – $485K a yearScience & research

    Anthropic's Safeguards organization builds the policies, evaluations, and enforcement systems that keep our models from contributing to catastrophic harm. We are hiring a manager to lead the research engineering team responsible for biological safety: the evaluations, datasets,…

  • Octant Bio · Emeryville, California, United States

    Mid level$150K – $190K a yearScience & research

    We are seeking a scientist with cheminformatics expertise to join our dynamic and multidisciplinary research team. A core focus of your role will be to guide assay development and evaluate the resulting data using chemical reasoning, expanding the capabilities of the Octant…

  • OpenAI · San Francisco, California, United States

    Full-timeMid level$295K – $500K a yearScience & research

    The Interpretability team studies internal representations of deep learning models. We are interested in using representations to understand model behavior, and in engineering models to have more understandable representations. We are particularly interested in applying our…

  • Head of Research

    2 months ago

    Ambral · New York, United States +1

    On-siteFull-timeDirector$250K – $400K a yearScience & research

    Ambral Labs helps enterprises own the intelligence behind their most important workflows.

  • Braze · San Francisco, California, United States

    Lead / staff$184K – $299.8K a yearScience & research

    Braze is seeking a Staff Applied Scientist to join our Predictive and Generative AI (PGAI) team. The team's mission is to deliver a truly engaging and personalized customer experience through the creation of ML and AI enhanced marketing solutions. We own those solutions end to…

  • Apollo Research · London, England, United Kingdom +1

    On-siteFull-timeMid level$204K – $385K a yearScience & research

    Join our new AGI safety product team and help transform AI control research into practical tools that directly reduce risks from AI. As an Research Scientist (Control), you’ll work closely with Marius (CEO & currently leads the monitoring efforts), other control researchers and…

  • BillionToOne · Menlo Park, California, United States

    Full-timeDirector$250.2K – $272K a yearScience & research

    Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on…

Updated 07 Nov 2026 10:21 UTC from the OptiTalent job library.