Skip to main content

Twist Bioscience

Business Lead Data Governance Office

South San Francisco, California, United States

Location
South San Francisco, California, United States
Work
Not stated
Employment
Not stated
Level
Lead / staff
Function
Data & AI
Pay
$130.7K – $192.2K a year
Posted
2 weeks ago

About the role

Business Lead Data Governance Office (Hybrid in South San Francisco, CA)

Summary

Reporting directly to the Director of Business Intelligence, the SAP Master Data

Governance (MDG) Lead will provide business processes expertise to the end-to-end

architecture, implementation, and operational strategy of our enterprise master data ecosystem.

In this role, you will bridge technical execution, analytics strategy and business

process—helping to implement the SAP MDG platform, creating data quality rules, and initially

establishing a SAP Data Governance Office to ensure high data integrity, seamless reporting,

and single-source-of-truth analytics across the organization.

Key Responsibilities

SAP MDG Build & Technical Architecture

  • Participate and add expertise to the end-to-end implementation and configuration of SAP MDG domains (Business Partner, Customer/Vendor, Material, at a later time Financials).
  • Design custom data models, UI floorplans (FPM), change request workflows (BRF+), and Data Replication Frameworks (DRF).
  • Partner with BI and enterprise architecture teams to integrate MDG with SAP S/4HANA, analytics platforms, data warehouses, and downstream legacy systems.

Rule Creation & Data Quality Management

  • Define and enforce data validation rules, duplicate check algorithms, and business logic within the SAP MDG platform.
  • Establish automated data profiling, continuous remediation processes, and data quality scoring across core master data domains.
  • Define and monitor data governance KPIs, completion cycle times, and data health dashboards in alignment with reporting goals.

Governance Office & Stewardship Leadership

  • Build and formalize the Enterprise Data Governance Office, defining its charter, operating model, and cross-functional council.
  • Establish enterprise data stewardship frameworks, defining clear roles (Data Owners, Stewards, Custodians) and approval matrices.
  • Author data policies, standard operating procedures (SOPs), data dictionary standards, and data lineage documentation.
  • Partner with the Director of Business Intelligence to align data governance frameworks with business reporting, analytics strategy, and regulatory compliance.

Qualifications & Requirements

  • Bachelor’s degree in Computer Science, Information Systems, Business Intelligence, or a related field.
  • 8+ years Experience in SAP Data Management, with 4+ years leading full-lifecycle SAP MDG implementations.
  • Proven track record in both direct and indirect management.
  • Successful collaboration experience is a must.
  • Proven track record of establishing and managing a Data Governance Office and operationalizing data stewardship models.
  • Solid understanding of how master data governance directly impacts BI reporting, data warehousing, and enterprise analytics.

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.

San Francisco Bay Area Pay Range

$130,678—$192,178 USD

Source

Posted by Twist Bioscience on their own hiring page, job-boards.greenhouse.io. OptiTalent shows it as published, read 07 Nov 2026 03:29 UTC; the original is the reference.

View the original ad ↗

More at Twist Bioscience

  • Twist Bioscience · Quincy, Massachusetts, United States

    TemporaryEntry level$24.00 – $26.00 an hourTrades & logistics

    We are seeking a motivated, detail-oriented Manufacturing Associate to assist with antibody characterization assays and/or purification workflows within in vivo antibody discovery campaigns and high-throughput antibody production, characterization, and developability projects.…

  • Twist Bioscience · South San Francisco, California, United States

    Mid level$24.50 – $27.50 an hourOperations

    High school diploma or general education degree (GED).; 2 or more years of relevant experience in a high-volume manufacturing environment.; Experience in roles where attention to detail, accuracy, and documentation are critical to success.; Experience with order fulfillment…

  • Twist Bioscience · EUR, United States

    RemoteMid levelLegal & compliance

    Either fully qualified solicitor with at least 1-year PQE, or 4-7 years relevant contractual or commercial experience (ideally with a LLB (or equivalent) but not mandatory) at a major law firm or in-house legal department at a biotech, pharma or other life sciences company.;…

  • Twist Bioscience · United States

    RemoteLead / staff$132K – $167K a yearPeople & HR

    Twist is hiring a Staff Recruiter to own hiring for our Commercial organization: Sales, Marketing, Business Development and Commercial Operations, plus select roles in other functions. This is a senior individual contributor role for a recruiter who already operates as a…